BHLHE22 Antikörper (N-Term)

Produktnummer ABIN1105525

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch BHLHE22 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh) und Huhn.

Kurzübersicht für BHLHE22 Antikörper (N-Term) (ABIN1105525)

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BHLHE22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BHLHE22 Antikörper

Bindungsspezifität: N-Term

Sequenz: LPAGAALCLK YGESASRGSV AESSGGEQSP DDDSDGRCEL VLRAGVADPR

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, ZebrafishSpecies reactivity (tested):Human

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-BHLHB5 antibody: synthetic peptide directed towards the N terminal of human BHLHB5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu BHLHE22

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Andere Bezeichnung: BHLHB5 / BHLHE22

Hintergrund: BHLHB5 is a member of family of basic helix-loop-helix (bHLH) transcription factors. Members of this family have been implicated in many aspects of neural development, including cell growth, differentiation, and cell migration. BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA.Synonyms: Class B basic helix-loop-helix protein 5, Class E basic helix-loop-helix protein 22, TNRC20, Trinucleotide repeat-containing gene 20 protein

Gen-ID: 27319

NCBI Accession: NP_689627